| Region | Level | Region Chair | Instrument | Name | School |
| 5 | JR | 01 | Flute | Jakierah Eagle | Dillon Middle School |
| 5 | JR | 02 | Flute | Eliza Dennis | Daniel Island Middle School |
| 5 | JR | 03 | Flute | Isaque DaCosta | Westview Middle School (Goose Creek) |
| 5 | JR | 04 | Flute | Emily Moore | Marrington Middle School |
| 5 | JR | 05 | Flute | Emma Ryen | Ten Oaks Middle School |
| 5 | JR | 06 | Flute | Kendall Williamson | Ten Oaks Middle School |
| 5 | JR | 07 | Flute | Lily Green | Southside Middle School |
| 5 | JR | 08 | Flute | Naomi Reed | Georgetown Middle School |
| 5 | JR | 09 | Flute | Maliyah Crowe | Sangaree Middle School |
| 5 | JR | 10 | Flute | Joshua Olmeda | Sangaree Middle School |
| 5 | JR | 11 | Flute | Savanna Steen | Socastee Middle School |
| 5 | JR | 12 | Flute | Genesis Gooden | John W. Moore Middle School |
| 5 | JR | A01 | Flute | Johalia Brown | Dillon Middle School |
| 5 | JR | A02 | Flute | Maria Gomez | Dillon Middle School |
| 5 | JR | 01 | Oboe | Gavril Tiburcio | Latta High School |
| 5 | JR | 02 | Oboe | Sophia Conn | Sangaree Middle School |
| 5 | JR | 03 | Oboe | Wyatt Lee | Westview Middle School (Goose Creek) |
| 5 | JR | 04 | Oboe | Laura Perry | Philip Simmons Middle School |
| 5 | JR | A01 | Oboe | Hope Holmes | Hanahan Middle School |
| 5 | JR | A02 | Oboe | Karissa Thompson | Cane Bay Middle School |
| 5 | JR | 01 | Bassoon | Bryce Hatfield | Westview Middle School (Goose Creek) |
| 5 | JR | 02 | Bassoon | Riley Kitchens | Marrington Middle School |
| 5 | JR | 01 | Clarinet | Patrick Eggen | John W. Moore Middle School |
| 5 | JR | 02 | Clarinet | Victoria Holmes | Westview Middle School (Goose Creek) |
| 5 | JR | 03 | Clarinet | Anna Baumgarner | Westview Middle School (Goose Creek) |
| 5 | JR | 04 | Clarinet | Jayla Kennedy-Blue | Williams Middle School |
| 5 | JR | 05 | Clarinet | Lilly Stone | Sangaree Middle School |
| 5 | JR | 06 | Clarinet | Abril Alvarez Samaniego | Hanahan Middle School |
| 5 | JR | 07 | Clarinet | Katie Griffin | Daniel Island Middle School |
| 5 | JR | 08 | Clarinet | Saqqara Hicks | Darlington Middle School |
| 5 | JR | 09 | Clarinet | Hayden Foley | John W. Moore Middle School |
| 5 | JR | 10 | Clarinet | William Buchheit | Marrington Middle School |
| 5 | JR | 11 | Clarinet | Dominic Troutman | Westview Middle School (Goose Creek) |
| 5 | JR | 12 | Clarinet | William Owen | North Myrtle Beach Middle School |
| 5 | JR | 13 | Clarinet | Casey Musollari | Ten Oaks Middle School |
| 5 | JR | 14 | Clarinet | Nathan Benton | Georgetown Middle School |
| 5 | JR | 15 | Clarinet | John Buie | Socastee Middle School |
| 5 | JR | 16 | Clarinet | Tristan Thompson | Cane Bay Middle School |
| 5 | JR | 17 | Clarinet | Shanya Blanchard | Marrington Middle School |
| 5 | JR | 18 | Clarinet | Amille Malloy | Dillon Middle School |
| 5 | JR | 19 | Clarinet | Tanna Adams | Chesterfield-Ruby Middle School |
| 5 | JR | 20 | Clarinet | Jalynn Harris | Long Middle School |
| 5 | JR | 21 | Clarinet | Daniel Silva | Marrington Middle School |
| 5 | JR | 22 | Clarinet | Siqi Fang | Hanahan Middle School |
| 5 | JR | 23 | Clarinet | Abigail Dukes | Waccamaw Middle School |
| 5 | JR | 24 | Clarinet | Savannah Long | Loris Middle School |
| 5 | JR | A01 | Clarinet | Adrian Grate | Waccamaw Middle School |
| 5 | JR | A02 | Clarinet | Riley Howard | Philip Simmons Middle School |
| 5 | JR | A03 | Clarinet | Aiden Boschert | Marrington Middle School |
| 5 | JR | A04 | Clarinet | Giovanny Martinez | Forestbrook Middle School |
| 5 | JR | A05 | Clarinet | Ashlen Miller | Socastee Middle School |
| 5 | JR | A06 | Clarinet | Awaab Kamil | Hanahan Middle School |
| 5 | JR | A07 | Clarinet | Ellis Fetten | Daniel Island Middle School |
| 5 | JR | 01 | Bass Clarinet | Yasmine Glaoui | Socastee Middle School |
| 5 | JR | 02 | Bass Clarinet | Charlize Fincher | Sangaree Middle School |
| 5 | JR | 03 | Bass Clarinet | Caroline D’Aguiar | Daniel Island Middle School |
| 5 | JR | 04 | Bass Clarinet | Avery Jackson | Marrington Middle School |
| 5 | JR | A01 | Bass Clarinet | Emmalynn Wagner | North Myrtle Beach Middle School |
| 5 | JR | A02 | Bass Clarinet | John Frisby | North Myrtle Beach Middle School |
| 5 | JR | 01 | Contra Clarinet | Isabella Sears | Ten Oaks Middle School |
| 5 | JR | 01 | Alto Sax | Audrianna Amara | Hanahan Middle School |
| 5 | JR | 02 | Alto Sax | Jorge Martinez Zuniga | Hanahan Middle School |
| 5 | JR | 03 | Alto Sax | McKeithan Daniels | John W. Moore Middle School |
| 5 | JR | 04 | Alto Sax | Mitchell Bennett | Sangaree Middle School |
| 5 | JR | 05 | Alto Sax | Daniel Vargas | St. James Middle School |
| 5 | JR | 06 | Alto Sax | Kristopher McGee | Westview Middle School (Goose Creek) |
| 5 | JR | A01 | Alto Sax | Oscar Martinez Lemus | North Myrtle Beach Middle School |
| 5 | JR | A02 | Alto Sax | Trever Brown | Berkeley Middle School |
| 5 | JR | A03 | Alto Sax | Andre Ashley | Sneed Middle School |
| 5 | JR | 01 | Tenor Sax | Matthew Tchoryk | Philip Simmons Middle School |
| 5 | JR | 02 | Tenor Sax | Isabella Balog | Philip Simmons Middle School |
| 5 | JR | A1 | Tenor Sax | Ean Bane | North Myrtle Beach Middle School |
| 5 | JR | 01 | Bari Sax | Madison Tumminia | Ten Oaks Middle School |
| 5 | JR | A01 | Bari Sax | Chandler Bates | Sneed Middle School |
| 5 | JR | 01 | Trumpet | Angello Gonzalez | Sangaree Middle School |
| 5 | JR | 02 | Trumpet | Matthew Perry | Philip Simmons Middle School |
| 5 | JR | 03 | Trumpet | Ishaan Patel | Philip Simmons Middle School |
| 5 | JR | 04 | Trumpet | Lauren Tinnea | Westview Middle School (Goose Creek) |
| 5 | JR | 05 | Trumpet | Jackson Tucker | Westview Middle School (Goose Creek) |
| 5 | JR | 06 | Trumpet | Caio Andrecioli | Long Middle School |
| 5 | JR | 07 | Trumpet | Christian Blease | Philip Simmons Middle School |
| 5 | JR | 08 | Trumpet | Anthony Elya | St. Anthony Catholic School |
| 5 | JR | 09 | Trumpet | Cameron Ellison | Dillon Middle School |
| 5 | JR | 10 | Trumpet | Candido Rosales-Perez | Loris Middle School |
| 5 | JR | 11 | Trumpet | Sophia Ligon | Daniel Island Middle School |
| 5 | JR | 12 | Trumpet | Eva Washington | Westview Middle School (Goose Creek) |
| 5 | JR | 13 | Trumpet | Nick Beck | Ocean Bay Middle School |
| 5 | JR | 14 | Trumpet | Crystal Nguyen | Hanahan Middle School |
| 5 | JR | 15 | Trumpet | Jayla Wigfall | Sangaree Middle School |
| 5 | JR | 16 | Trumpet | Jamison Mumford | Williams Middle School |
| 5 | JR | A01 | Trumpet | Lena Rafferty | Hanahan Middle School |
| 5 | JR | A02 | Trumpet | Hannah Quindo | Hanahan Middle School |
| 5 | JR | A03 | Trumpet | Jamiya Jones | Dillon Middle School |
| 5 | JR | A04 | Trumpet | Jack Hartnett | Hanahan Middle School |
| 5 | JR | A05 | Trumpet | Jake Heldreth | Aynor Middle School |
| 5 | JR | A06 | Trumpet | Ivan Morley | Jonakin Middle School |
| 5 | JR | A07 | Trumpet | Heath Mew | Latta High School |
| 5 | JR | A08 | Trumpet | Isaiah Daniels | North Myrtle Beach Middle School |
| 5 | JR | 01 | Horn | James Hazelwood | College Park Middle School |
| 5 | JR | 02 | Horn | Henry Odgers | Westview Middle School (Goose Creek) |
| 5 | JR | 03 | Horn | Georgia Hand | Ten Oaks Middle School |
| 5 | JR | 04 | Horn | Carlee Capps | North Myrtle Beach Middle School |
| 5 | JR | 05 | Horn | Jacob Erese | Hartsville Middle School |
| 5 | JR | 06 | Horn | Finn Long | Georgetown Middle School |
| 5 | JR | 07 | Horn | Neriah Gordon-Scott | Dillon Middle School |
| 5 | JR | 08 | Horn | Brayden Stillwagon | Ocean Bay Middle School |
| 5 | JR | A01 | Horn | Zachary Reaves | John W. Moore Middle School |
| 5 | JR | 01 | Trombone | Rosie Leggett | Hanahan Middle School |
| 5 | JR | 02 | Trombone | Oliver Thomas | St. Anthony Catholic School |
| 5 | JR | 03 | Trombone | Lana Ames | Westview Middle School (Goose Creek) |
| 5 | JR | 04 | Trombone | Robinson Mendez | Aynor Middle School |
| 5 | JR | 05 | Trombone | Arianna Solorio | Sangaree Middle School |
| 5 | JR | 06 | Trombone | Gwyneth Meador | Cane Bay Middle School |
| 5 | JR | 07 | Trombone | Jacob Nunn | Sangaree Middle School |
| 5 | JR | 08 | Trombone | Jadyn Christman | Sangaree Middle School |
| 5 | JR | 09 | Trombone | Keandre Ham | Williams Middle School |
| 5 | JR | A01 | Trombone | Brooklyn Washington | Philip Simmons Middle School |
| 5 | JR | A02 | Trombone | Sam Cott | Hanahan Middle School |
| 5 | JR | A03 | Trombone | Amielia Pauls | Forestbrook Middle School |
| 5 | JR | A04 | Trombone | Nathon Hammond | Dillon Middle School |
| 5 | JR | A05 | Trombone | Julia Reilly | Philip Simmons Middle School |
| 5 | JR | 01 | Euphonium | Nathan Ainsworth | Long Middle School |
| 5 | JR | 02 | Euphonium | Shakhana Boone | Dillon Middle School |
| 5 | JR | 03 | Euphonium | Sam Luciani | Sangaree Middle School |
| 5 | JR | 04 | Euphonium | Joseph Coon | Berkeley Middle School |
| 5 | JR | A01 | Euphonium | Kenniah Tucker | Spaulding Middle School |
| 5 | JR | A02 | Euphonium | Axel Crenades | St. James Middle School |
| 5 | JR | 01 | Tuba | Erik Ortuno-Martinez | Sangaree Middle School |
| 5 | JR | 02 | Tuba | DeClan Hawthorne | Westview Middle School (Goose Creek) |
| 5 | JR | 03 | Tuba | Dasani McLaurin | Dillon Middle School |
| 5 | JR | 04 | Tuba | Jonah Karen | Daniel Island Middle School |
| 5 | JR | 05 | Tuba | Maeghan Hodges | St. Anthony Catholic School |
| 5 | JR | 06 | Tuba | Joelie Propst | St. James Middle School |
| 5 | JR | 01 | Percussion | Freddy Pleis | Marrington Middle School |
| 5 | JR | 02 | Percussion | Blake Johnson | Marrington Middle School |
| 5 | JR | 03 | Percussion | Naomi Driskell | Hanahan Middle School |
| 5 | JR | 04 | Percussion | Matthew Carter | North Myrtle Beach Middle School |
| 5 | JR | 05 | Percussion | Dawson Hatcher | Long Middle School |
| 5 | JR | 06 | Percussion | Jackson Swinyer | Hanahan Middle School |
| 5 | JR | 07 | Percussion | Leo Sarmiento | Williams Middle School |
| 5 | JR | A01 | Percussion | Jenna Zamrik | North Myrtle Beach Middle School |
| 5 | JR | A02 | Percussion | Reese Tuohy | Ten Oaks Middle School |
| 5 | JR | A03 | Percussion | Julianna Thompson | Marrington Middle School |
| 5 | JR | A04 | Percussion | NaShea Long | Berkeley Middle School |
| 5 | JR | 01 | Timpani | Eli Seif | St. Anthony Catholic School |
| 5 | JR | A01 | Timpani | Ryan Carswell | Philip Simmons Middle School |